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Recombinant Human Ig lambda constant 2 (C-6His)

Product Specifications

Background

Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. It contains one Ig-like domain (aa 7-100) and generates a disulfide bond with an IgH chain via Cys104.

Abbreviation

Ig lambda constant 2

Synonyms

IGLC; IGLC2; Ig Lambda C Domain; Ig lambda constant 2; Immunoglobulin Lambda Constant 2; MGC20392; MGC45681; immunoglobulin lambda constant 2 (Kern-Oz- marker)

UniProt

P0DOY2

Accession Number

P0DOY2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly1-Ser106

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.1 kDa

Observed Molecular Weight

16 kDa

Species

Human

Available Sizes

Frequently Asked Questions

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