Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)

Product Specifications

Background

NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.

Abbreviation

HLA-A*0201 NY-ESO-1 complex

Synonyms

HLA-A*0201 NY-ESO-1 complex Protein; MHC; MY-ESO-1

UniProt

P61769; P01892

Accession Number

P61769&P01892

Expression System

HEK293 Cells

Tag

C-His

Sequence

SLLMWITQC&Ile21-Met119&Gly25-Ile308 (Ala269Val)

Field of Research

Microbiology; immunology; Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.