Recombinant Human CD3E&CD3G Heterodimer (C-Fc-6His&C-Fc-Flag)

Product Specifications

Background

T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Abbreviation

CD3E&CD3G Heterodimer

Synonyms

CD3 epsilon & CD3 gamma; CD3E & CD3G; CD3E & CD3G Heterodimer; IMD18; T3E; TCRE

UniProt

P07766; P09693

Accession Number

P07766&P09693

Expression System

HEK293 Cells

Tag

C-Fc-Flag & C-Fc-His

Sequence

Asp23-Asp126&Gln23-Ser116

Field of Research

Immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.