Recombinant Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-6His-Avi) Biotinylated
Product Specifications
Background
The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR) ) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR) . Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.
Abbreviation
LILRB1; ILT2; CD85j
Synonyms
CD85 Antigen-Like Family Member J; CD85j; ILT-2; ILT2; Immunoglobulin-Like Transcript 2; LILRB1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; MIR-7; Monocyte/Macrophage Immunoglobulin-Like Receptor 7
UniProt
D9IDM8
Accession Number
D9IDM8
Expression System
HEK293 Cells
Conjugation
Biotinylated
Tag
C-His-Avi
Sequence
Gly24-His458
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
50.0 kDa
Observed Molecular Weight
70-90 kDa
Species
Human
Available Sizes
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