Retinol Binding Protein (Native Lyophilized)

<strong>Retinol Binding Protein (Native Lyophilized)</strong>_x000D_ <strong>Catalog number:</strong> B2010386_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 21 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized powder_x000D_ <strong>Appearance:</strong> White powder_x000D_ <strong>Applications:</strong> native RBP protein with mutiple functions that include binding retinol (a compound with key roles in the regulation of gene expression). Serum concentrations of RBP can be used to monitor liver function, malnutrition, Cystic Fibrosis and renal function._x000D_ <strong>Storage:</strong> 2-8C_x000D_ <strong>Keywords:</strong> RBP, Human RBP, hRBP_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Perduca M, Nicolis S, Mannucci B, Galliano M, Monaco HL. Human plasma_x000D_ retinol-binding protein (RBP4) is also a fatty acid-binding protein. Biochim_x000D_ Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):458-466._x000D_ _x000D_ 2: Est CB, Murphy RM. Retinol binding protein IV purified from Escherichia coli_x000D_ using intein-mediated cleavage as a suitable replacement for serum sources._x000D_ Protein Expr Purif. 2020 Mar;167:105542._x000D_ _x000D_ 3: Barletta GP, Franchini G, Corsico B, Fernandez-Alberti S. Fatty Acid and_x000D_ Retinol-Binding Protein: Unusual Protein Conformational and Cavity Changes_x000D_ Dictated by Ligand Fluctuations. J Chem Inf Model. 2019 Aug 26;59(8):3545-3555._x000D_ _x000D_ 4: Zanotti G, Berni R. Plasma retinol-binding protein: structure and_x000D_ interactions with retinol, retinoids, and transthyretin. Vitam Horm._x000D_ 2004;69:271-95._x000D_ _x000D_ 5: Monaco HL. The transthyretin-retinol-binding protein complex. Biochim Biophys_x000D_ Acta. 2000 Oct 18;1482(1-2):65-72._x000D_ _x000D_ 6: Rask L, Anundi H, Böhme J, Eriksson U, Fredriksson A, Nilsson SF, Ronne H,_x000D_ Vahlquist A, Peterson PA. The retinol-binding protein. Scand J Clin Lab Invest_x000D_ Suppl. 1980;154:45-61._x000D_ _x000D_ 7: Raghu P, Sivakumar B. Interactions amongst plasma retinol-binding protein,_x000D_ transthyretin and their ligands: implications in vitamin A homeostasis and_x000D_ transthyretin amyloidosis. Biochim Biophys Acta. 2004 Dec 1;1703(1):1-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/12553421/">8: Gaetani S, Bellovino D, Apreda M, Devirgiliis C. Hepatic synthesis,_x000D_ maturation and complex formation between retinol-binding protein and_x000D_ transthyretin. Clin Chem Lab Med. 2002 Dec;40(12):1211-20. </a>_x000D_ _x000D_ <strong>Products Related to Retinol Binding Protein (Native Lyophilized)</strong><a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>