Recombinant Human 4-1BB/TNFRSF9 Protein (mFc Tag)
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 9 (TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL; and possibly active during T cell activation.
Abbreviation
4-1BB; TNFRSF9
Synonyms
4-1BB ligand receptor; CD137; CDw137; ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNFRSF9
UniProt
Q07011
Accession Number
Q07011
Expression System
HEK293 Cells
Tag
C-mFc
Sequence
Leu24-Gln186
Field of Research
Cell biology; Cancer; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
43.9 kDa
Observed Molecular Weight
50-70 kDa
Species
Human
Available Sizes
Documents
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