Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)

Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.

ACVRL1; ACVRLK1; ALK-1; ALK1; Activin Receptor-Like Kinase 1; HHT; HHT2; ORW2; SKR3; Serine/Threonine-Protein Kinase Receptor R3; TGF-B Superfamily Receptor Type I; TSR-I

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.