Recombinant Human CD38 Protein (Fc Tag)
Product Specifications
Background
CD38; also called ADP-ribosyl cyclase; is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes; osteoclasts; and in cardiac; pancreatic; liver and kidney cells. Through its production of cyclic ADP-ribose; CD38 modulates calcium-mediated signal transduction in many types of cells; including neutrophils and pancreatic beta cells.
Abbreviation
CD38
Synonyms
ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; CD38; CD38 antigen; CD38 molecule; Cyclic ADP-ribose hydrolase 1
UniProt
P28907
Accession Number
P28907
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Val43-Ile300
Field of Research
Cancer; immunology; metabolism; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/qalh58
Product MSDS
https://789.bio/eb/WfbrXT
Calculated Molecular Weight
57.0 kDa
Observed Molecular Weight
70-90 kDa
Species
Human
Available Sizes
Curated Selection
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