Recombinant Human CEACAM1/CD66a Protein (His Tag)
Product Specifications
Background
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
Abbreviation
CEACAM1; CD66a
Synonyms
BGP; BGP-1; BGP1; Biliary Glycoprotein 1; CD66a; CEACAM1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
UniProt
P13688
Accession Number
P13688
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln35-Gly428
Field of Research
Tags & Cell Markers; Microbiology; Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
44.3 kDa
Observed Molecular Weight
60-90 kDa
Species
Human
Available Sizes
Documents
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