Recombinant Human CCL17/TARC Protein (His Tag)
Product Specifications
Background
C-C motif chemokine 17 (CCL17) is a novel CC chemokine, it belongs to the intercrine beta (chemokine CC) family. CCL17 is expressed at high levels in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Among CC chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1 alpha, MIP-1 beta, MCP-1, MCP-2 and MCP-3. CCL17 has been identified to be Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. CCL17 plays a role in T-cell development in thymus and in trafficking and activation of mature T-cells.
Abbreviation
CCL17; TARC
Synonyms
ABCD-2; C-C motif chemokine 17; CC chemokine TARC; CCL17; MGC138273; SCYA17MGC138271; Small-inducible cytokine A17; T cell-directed CC chemokine; TARC; TARCA-152E5.3; Thymus an; chemokine (C-C motif) ligand 17; member 17; small inducible cytokine subfamily A (Cys-Cys)
UniProt
Q92583
Accession Number
Q92583
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala24-Ser94
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/t54o4g
Product MSDS
https://789.bio/eb/mnrLOG
Calculated Molecular Weight
9.1 kDa
Observed Molecular Weight
13 kDa
Species
Human
Available Sizes
Curated Selection
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