Recombinant Human Erythropoietin R/EPOR Protein (Fc Tag)
Selected Variant
PKSH033686-01
Size: 10 µg
Product Specifications
Background
Erythropoietin (Epo) ; a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R) . The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.
Abbreviation
Erythropoietin R; EPOR
Synonyms
EPO-R; EpoR; Erythropoietin R; MGC138358; Platelet Receptor EPO-R; erythropoietin receptor
UniProt
P19235
Accession Number
P19235
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Ala25-Pro250
Field of Research
Signal Transduction; Cardiovascular; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
55-75 kDa
Species
Human
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