Recombinant Human Erythropoietin R/EPOR Protein (Fc Tag)

Product Specifications

Background

Erythropoietin (Epo) ; a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R) . The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

Abbreviation

Erythropoietin R; EPOR

Synonyms

EPO-R; EpoR; Erythropoietin R; MGC138358; Platelet Receptor EPO-R; erythropoietin receptor

UniProt

P19235

Accession Number

P19235

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ala25-Pro250

Field of Research

Signal Transduction; Cardiovascular; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.