Recombinant Human FABP4/A-FABP Protein (His Tag)
Product Specifications
Background
Fatty Acid-Binding Protein 4 (FABP4) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small; highly conserved; cytoplasmic proteins that bind long-chain fatty acids. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. FABP4 is thought to participate in Lipid transport protein in adipocytes. FABP4 binds to the long chain fatty acids and retinoic acid; delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. FABP4 modulates inflammatory responses and cholesterol ester accumulation. FABP4 is a plasma marker of metabolic disturbances in HIV-infected patients; and therefore; could serve to guide therapeutic intervention in this group of patients.
Abbreviation
FABP4; A-FABP
Synonyms
A-FABP; AFABP; ALBP; Adipocyte Lipid-Binding Protein; Adipocyte-Type Fatty Acid-Binding Protein; Fatty Acid-Binding Protein 4; Fatty Acid-Binding Protein Adipocyte; HEL-S-104; aP2
UniProt
P15090
Accession Number
P15090
Expression System
E.coli
Tag
N-His
Sequence
Cys2-Ala132
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/dkktep
Product MSDS
https://789.bio/eb/aDaXjT
Calculated Molecular Weight
16.9 kDa
Observed Molecular Weight
15 kDa
Species
Human
Available Sizes
Curated Selection
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