Recombinant Human FABP6/I-BABP Protein (His Tag)
Product Specifications
Background
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level) . Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. FABP6 plays a role in fatty acid uptake, transport, and metabolism. FABP6 stimulates gastric acid and pepsinogen secretion. It seems to be able to bind to bile salts and bilirubins.
Abbreviation
FABP6; I-BABP
Synonyms
FABP6; Fatty Acid-Binding Protein 6; GT; Gastrotropin; I-15P; I-BABP; ILBP; ILLBP; Ileal Lipid-Binding Protein; Intestinal 15 kDa Protein; Intestinal Bile Acid-Binding Protein
UniProt
P51161
Accession Number
AAH22489.1
Expression System
E.coli
Tag
N-His
Sequence
Met1-Ala128
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
16.6 kDa
Observed Molecular Weight
15 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 0.5mM DTT, 50% Glycerol, pH 8.0.
Species
Human
Available Sizes
Documents
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