Recombinant Human FGL1 Protein (mFc Tag)
Product Specifications
Background
Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1) ; is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
Abbreviation
FGL1
Synonyms
FGL1; Fibrinogen-like protein 1; HFREP-1; HP-041; Hepassocin; LFIRE-1
UniProt
Q08830
Accession Number
Q08830
Expression System
HEK293 Cells
Tag
C-mFc
Sequence
Leu23-Ile312
Applications
ELISA
Field of Research
Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/pmqiu1
Product MSDS
https://789.bio/eb/00evDO
Calculated Molecular Weight
60.6 kDa
Observed Molecular Weight
60-65 kDa
Species
Human
Available Sizes
Curated Selection
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