Recombinant Human IFN-λ1/IL-29 Protein (His Tag)

Interleukin-29 (IL-29) is a secreted protein which belongs to the IL-28/IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10R beta) and an orphan class II receptor chain, designated IL-28R alpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

IFN-lambda; Interleukin; ytokine Zcyto; Cytokine Zcyto; IFNL; ZCYTO; IFN-λ; lambda; Cytokine Zcyto21; IFN-lambda-1; IFN-λ1; IL-29; interferon; interferon lambda 1; Interferon lambda-1; Interleukin-29; lambda 1; ytokine Zcyto21; IL29; ZCYTO21; IFNL1

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.