Recombinant Human IL-1R8/IL1RAPL1 Protein (His Tag)

Product Specifications

Background

Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

Abbreviation

IL-1R8; IL1RAPL1

Synonyms

IL1R; OPHN; TIGIRR; MRX; IL1RAPL1; IL1R8; IL1RAPL; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2; IL1RAPL-1; IL-1RAPL-1; IL-1-RAPL-1; Interleukin-1 Receptor Accessory Protein-Like 1; Oligophrenin-4; Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2; X-Linked Interleukin-1 Receptor Accessory Protein-Like 1

UniProt

Q9NZN1

Accession Number

Q9NZN1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu19-Val360

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.