Recombinant Human IL7RA/CD127 Protein (Fc & His Tag)

Product Specifications

Background

Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

Abbreviation

IL7RA; CD127

Synonyms

CDW; IL7R; CD127; CDW127; IL-7R-alpha; IL7RA; ILRA; IL-7R; IL-7RA; IL-7Rα; Interleukin-7 receptor subunit alpha; IL-7Rα CD 127; CD127 antigen; IL 7R; IL 7R alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL7Ralpha; Interleukin 7 receptor; Interleukin 7 receptor alpha chain; Interleukin 7 receptor isoform H5 6

UniProt

P16871

Accession Number

P16871

Expression System

HEK293 Cells

Tag

C-Fc-His

Sequence

Glu21-Gly236

Field of Research

Immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.