Recombinant Human ACP1/LMW-PTP Protein (His Tag)
Product Specifications
Background
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of the PDGF receptor. In addition, LMW-PTP plays an important role in the regulation of physiological functions, such as stress resistance and synthesis of the polysaccharide capsule.
Abbreviation
ACP1; LMW-PTP
Synonyms
ACP1; Adipocyte Acid Phosphatase; HAAP; LMW-PTP; LMW-PTPase; Low Molecular Weight Cytosolic Acid Phosphatase; Low Molecular Weight Phosphotyrosine Protein Phosphatase; Red Cell Acid Phosphatase 1
UniProt
P24666
Accession Number
P24666-2
Expression System
E.coli
Tag
C-His
Sequence
Ala2-His158
Field of Research
Cell Biology, Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
19.0 kDa
Observed Molecular Weight
18 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Species
Human
Available Sizes
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