Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)
Product Specifications
Background
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
Abbreviation
NPPB
Synonyms
Gamma-Brain Natriuretic Peptide; NPPB; Natriuretic Peptides B
UniProt
P16860
Accession Number
P16860
Expression System
E.coli
Tag
N-His
Sequence
His27-His134
Field of Research
Signal Transduction; Cardiovascular; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
14.2 kDa
Observed Molecular Weight
16 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.4.
Species
Human
Available Sizes
Documents
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