Recombinant Human NRCAM Protein (Fc Tag)

Neuronal cell adhesion molecule (NRCAM) is a single-pass type I membrane protein , containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.

KIAA0343; Neuronal cell adhesion molecule; Neuronal surface protein Bravo; Ng-CAM-related; Nr-CAM; gCAM-related cell adhesion molecule; gCAM-related cell adhesion molecule ; hBravo

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.