Recombinant Human TNFSF4/OX40L Protein (mFc Tag)

Tumor necrosis factor ligand superfamily member 4 (TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells; T cells; dendritic cells and endothelial cells. OX40L binds to OX40 (CD134) ; a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional; it has been found association with systemic lupus erythematosus; no association with occurrence of atherosclerosis.

CD134L; CD252; GP34; Glycoprotein Gp34; OX-40; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFSF4; TXGP1; Tumor necrosis factor ligand superfamily member 4

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.