Recombinant Human CD31/PECAM1 Protein (Fc Tag)
Product Specifications
Background
Semaphorin-4G is the least characterized of the seven known Class 4 transmembrane semaphorin glycoproteins. Class 4 semaphorins play multiple roles in cell attraction or repulsion, such as development of nerve pathways in the brain, promoting or inhibiting proliferation, in some cases organizing immune cell interactions. Semaphorin-4G can be expressed early in development in the central and peripheral nervous systems and in sensory ograns, such as cochlea, olfactory epithelium, vomeronasal organ and retina. In adults, Semaphorin-4G can be found in liver, kidney and brain. The human Semaphorin-4G precursor consists of a 17 amino acids signal sequence, a 658 amino acids extracellular domain, a 21 amino acids transmembrane domain, a 142 amino acids cytoplasmic domain with one Ser/Thr phosphorylation site.
Abbreviation
CD31; PECAM1
Synonyms
CD31; EndoCAM; GPIIA; PECA1; PECAM-1; PECAM1 ; Platelet endothelial cell adhesion molecule
UniProt
P16284
Accession Number
AAH22512.1
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Gln28-Lys601
Field of Research
Signal Transduction; Cardiovascular; Cancer; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
91.6 kDa
Observed Molecular Weight
110-130 kDa
Species
Human
Available Sizes
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items