Recombinant Human CD155/PVR/NECL5 Protein (Fc Tag)
Product Specifications
Background
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV) ; an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.
Abbreviation
CD155; PVR; NECL5
Synonyms
CD155; NECL-5; Nectin-Like Protein 5; PVR; PVS; Poliovirus Receptor
UniProt
P15151
Accession Number
P15151
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Trp21-Asn343
Field of Research
Microbiology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/h8dho0
Product MSDS
https://789.bio/eb/44SyH0
Calculated Molecular Weight
62.2 kDa
Observed Molecular Weight
80-120 kDa
Species
Human
Available Sizes
Curated Selection
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