Recombinant Human S100A4 Protein (His Tag)
Product Specifications
Background
S100A4 is a member of the S100 family of proteins. The S100 family is further classified as a member of the EF-hand superfamily of Ca++-binding proteins. These participate in both calcium-dependent and calcium-independent protein-protein interactions. The hallmark of this superfamily is the EF-hand motif that consists of a Ca++-binding site flanked by two α-helices (helix E and helix F) that were originally identified in a right-handed model of carp muscle calcium-binding protein. Human S100A4 is 101 amino acids (aa) in length. It contains two EF hand domains, one between aa 12-47, and a second between aa 50-85. S100A4 activity has been associated with cell transformation. It seems likely this is either coincidental, or a consequence, rather than a cause of transformation.
Abbreviation
S100A4
Synonyms
18A2;42A; CAPL; Calvasculin; FSP1; MTS1; Metastasin; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100-A4; S100 calcium-binding protein A4; S100A4
UniProt
P26447
Accession Number
P26447
Expression System
E.coli
Tag
C-His
Sequence
Met1-Lys101
Field of Research
Signal Transduction; Cardiovascular; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/p9czap
Product MSDS
https://789.bio/eb/SOuDCS
Calculated Molecular Weight
12.6 kDa
Observed Molecular Weight
13 kDa
Species
Human
Available Sizes
Curated Selection
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