Recombinant Human Semaphorin 3A/SEMA3A Protein (His & Flag Tag)
Product Specifications
Background
Emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent; inhibiting axonal outgrowth; or as a chemoattractive agent; stimulating the growth of apical dendrites. In both cases; the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
Abbreviation
Semaphorin 3A; SEMA3A
Synonyms
Hsema-I; Hsema-III; SEMA1; SEMA3A; SEMAD; SemD; Sema III; Semad; Semaphorin III; coll-1
UniProt
Q14563
Accession Number
Q14563
Expression System
HEK293 Cells
Tag
N-His-Flag
Sequence
Lys26-Phe546
Field of Research
Cardiovascular; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/pdd048
Product MSDS
https://789.bio/eb/GGWLuL
Calculated Molecular Weight
61.3 kDa
Observed Molecular Weight
70-75 kDa
Species
Human
Available Sizes
Curated Selection
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