Recombinant Human CD96 Protein (His Tag)

Product Specifications

Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR) ; anectins and nectin-like protein family member serve to mediate cell-cell adhesion; cell migration; with the presence of an additional receptor; CD96. CD96 promotes NK cell adhesion to target cells expressing PVR; stimulates cytotoxicity of activated NK cells; and mediates acquisition of PVR from target cells.

Abbreviation

CD96

Synonyms

CD96; Cell surface antigen CD96; T cell-activated increased late expression protein; T-cell surface protein tactile

UniProt

P40200

Accession Number

P40200-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val22-Met503

Applications

BLI

Field of Research

Immunology, Stem Cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Loaded Human PVR-Fc on Protein A Biosensor, can bind Human CD96-His with an affinity constant of 0.12 uM as determined in BLI assay.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.