Recombinant Human CNDP1 Protein (His Tag)
Product Specifications
Background
Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain; serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1;10-o-phenantrolin. In addition; CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine) ; anserine; Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.
Abbreviation
CNDP1
Synonyms
Beta-Ala-His Dipeptidase; CN1; CNDP Dipeptidase 1; CNDP1; CPGL2; Carnosine Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; HsT2308; Serum Carnosinase
Accession Number
AAI13513.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Pro28-His507
Field of Research
Signal Transduction; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
54.9 kDa
Observed Molecular Weight
60-90 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Species
Human
Available Sizes
Documents
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