Recombinant Human Cathepsin Z Protein (His Tag)
Product Specifications
Background
Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.
Abbreviation
Cathepsin Z
Synonyms
CTSZ; Cathepsin P; Cathepsin X; Cathepsin Z
UniProt
Q9UBR2
Accession Number
Q9UBR2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly24-Val303
Field of Research
Tags & Cell Markers
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
32.5 kDa
Observed Molecular Weight
37-40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 4mM HCl.
Species
Human
Available Sizes
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