Recombinant Human Factor D Protein (His Tag)
Product Specifications
Background
Complement factor D; also known as adipsin; is a member of the chymotrypsin family of serine proteases; which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3; which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes; including immunity and inflammation.
Abbreviation
Factor D
Synonyms
ADIPSIN; ADN; Adipsin; C3 convertase activator; CFD; Complement factor D; DF; FACTOR D; PFD; Properdin factor D
UniProt
P00746
Accession Number
P00746
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ile26-Ala253
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
25.8 kDa
Observed Molecular Weight
28 kDa
Formulation
2
Species
Human
Available Sizes
Documents
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNCB2220-500 1x 500 µL
CD43 (T-Cell Marker) (rSPN/839), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
C3100 1 Each
LC-8 3500 Centrifuge with 8 x 15ml rotor, Max. Speed 3500 rpm, 120V
Sign In for Pricing
View Details 
BNC042177-100 1x 100 µL
DNA Ligase 1 (1A9), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details