Recombinant Human Factor D Protein (His Tag)
Product Specifications
Background
Complement factor D; also known as adipsin; is a member of the chymotrypsin family of serine proteases; which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3; which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes; including immunity and inflammation.
Abbreviation
Factor D
Synonyms
ADIPSIN; ADN; Adipsin; C3 convertase activator; CFD; Complement factor D; DF; FACTOR D; PFD; Properdin factor D
UniProt
P00746
Accession Number
P00746
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ile26-Ala253
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
25.8 kDa
Observed Molecular Weight
28 kDa
Formulation
2
Species
Human
Available Sizes
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6291010-01 0.1 mL
Dcc, CT (Dcc, Netrin receptor DCC, Tumor suppressor protein DCC) (MaxLight 650)
Ask
View Details 
MBS6291010-02 5x 0.1 mL
Dcc, CT (Dcc, Netrin receptor DCC, Tumor suppressor protein DCC) (MaxLight 650)
Ask
View Details