Recombinant Human LBP Protein (His Tag)
Product Specifications
Background
Lipopolysaccharide binding protein (LBP) is a plasma protein, belongs to a member of structurally and functionally related proteins which includes bactericidal permeability-increasing protein (BPI), plasma cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP) . It is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with BPI. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. Studies suggest that LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. Finally, t The LBP gene is found on chromosome 20, directly downstream of the BPI gene.
Abbreviation
LBP
Synonyms
BPIFD2; LBP; Lipopolysaccharide-Binding Protein
Accession Number
P18428
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala26-Val481
Field of Research
Microbiology; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
52.0 kDa
Observed Molecular Weight
64 kDa
Species
Human
Available Sizes
Curated Selection
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