Recombinant Human VAPB Protein (His Tag)
Product Specifications
Background
Vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer; and heterodimer with VAPA. It also interacts with VAMP1; VAMP2; HCV NS5A; NS5B; ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is involved in cellular calcium homeostasis regulation.
Abbreviation
VAPB
Synonyms
VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C; Vesicle-associated membrane protein-associated protein B/C
UniProt
O95292
Accession Number
O95292
Expression System
E.coli
Tag
C-His
Sequence
Ala2-Pro132
Field of Research
Signal Transduction, Cancer, Metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.0 kDa
Observed Molecular Weight
16 kDa
Species
Human
Available Sizes
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