Recombinant Human ASGR1/ASGPR1 Protein (His Tag)
Product Specifications
Background
Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.
Abbreviation
ASGR1; ASGPR1
Synonyms
ASGP-R 1; ASGPR 1; ASGR1; Asialoglycoprotein Receptor 1; C-Type Lectin Domain Family 4 Member H1; CLEC4H1; HL-1; Hepatic Lectin H1
UniProt
P07306
Accession Number
P07306
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln62-Ile291
Field of Research
Signal Transduction; Tags & Cell Markers
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/tptwdg
Product MSDS
https://789.bio/eb/HqPmD4
Calculated Molecular Weight
27.4 kDa
Observed Molecular Weight
34-48 kDa
Species
Human
Available Sizes
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