Recombinant Human ASGR1/ASGPR1 Protein (His Tag)

Product Specifications

Background

Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.

Abbreviation

ASGR1; ASGPR1

Synonyms

ASGP-R 1; ASGPR 1; ASGR1; Asialoglycoprotein Receptor 1; C-Type Lectin Domain Family 4 Member H1; CLEC4H1; HL-1; Hepatic Lectin H1

UniProt

P07306

Accession Number

P07306

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln62-Ile291

Field of Research

Signal Transduction; Tags & Cell Markers

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.