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Recombinant Human CADM3 Protein (His Tag)

Product Specifications

Background

Cell Adhesion Molecular Proteins are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix in the cell adhesion process. These proteins consists of three domains, an transmembrane domain, an intracellular domain that interacts with the cytoskeleton, and an extracellular domain that interacts with other CAMs of the same kind or with other CAMs or the extracellular matrix. Cell Adhesion Molecular 3 (CADM3) is a neural tissue-specific member of the nectin-like family of immunoglobulin superfamily. CADM3 interacts with EPB41L1 may regulate structure or function of cell-cell junctions. CADM3 has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3.

Abbreviation

CADM3

Synonyms

Brain Immunoglobulin Receptor; CADM3; Cell Adhesion Molecule 3; IGSF4B; IgSF4B; Immunoglobulin Superfamily Member 4B; NECL-1; NECL1; Nectin-Like Protein 1; SYNCAM3; SynCAM3; Synaptic Cell Adhesion Molecule 3; TSLC1-Like Protein 1; TSLL1

Accession Number

Q8N126

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asn25-His330

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

34.7 kDa

Observed Molecular Weight

35-42 kDa

Species

Human

Available Sizes

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