Recombinant Human IL-21R Protein (His Tag)
Product Specifications
Background
Interleukin-21 receptor is also known as IL-21 receptor; IL-21R; CD360. In humans; it is encoded by the IL21R gene. It belongs to the type I cytokine receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.
Abbreviation
IL-21R
Synonyms
UNQ; IL21R; CD360; NILR; CD360.; IL-21 receptor; IL-21R; Interleukin-21 receptor; UNQ3121; PRO10273; NILR
UniProt
Q9HBE5
Accession Number
Q9HBE5
Expression System
HEK293 Cells
Tag
C-His
Sequence
Cys20-Pro236
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/gxu9lp
Product MSDS
https://789.bio/eb/0irHqD
Calculated Molecular Weight
26.0 kDa
Observed Molecular Weight
40-55 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
