Recombinant Human FCRL1 Protein (His Tag)
Product Specifications
Background
Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
Abbreviation
FCRL1
Synonyms
CD307a; FCRH1; FCRL1; Fc Receptor Homolog 1; Fc Receptor-Like Protein 1; FcR-Like Protein 1; FcRH1; FcRL1; IFGP Family Protein 1; IFGP1; IRTA5; Immune Receptor Translocation-Associated Protein 5; hIFGP1
UniProt
Q96LA6
Accession Number
Q96LA6
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala17-Asn303
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
32.2 kDa
Observed Molecular Weight
39-50 kDa
Species
Human
Available Sizes
Documents
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