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Recombinant Human VSIG2 Protein (His Tag)

Product Specifications

Background

V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco) protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach; colon; prostate; trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families; including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2) ; CD4; CD80; and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM) ; in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1) . It shows expression in stomach and prostate by Northern blot; and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.

Abbreviation

VSIG2

Synonyms

CT-Like Protein; CTH; CTXL; Cortical Thymocyte-Like Protein; V-Set and Immunoglobulin Domain-Containing Protein 2; VSIG2

UniProt

Q96IQ7

Accession Number

Q96IQ7

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val24-Ala243

Field of Research

Cell Biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

24.2 kDa

Observed Molecular Weight

24-36 kDa

Species

Human

Available Sizes

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