Recombinant Human XPNPEP2 Protein (His Tag)
Product Specifications
Background
Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesn’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.
Abbreviation
XPNPEP2
Synonyms
Aminoacylproline Aminopeptidase; Membrane-Bound APP; Membrane-Bound AmP; Membrane-Bound Aminopeptidase P; X-Pro Aminopeptidase 2; XPNPEP2; Xaa-Pro Aminopeptidase 2; mAmP
UniProt
O43895
Accession Number
O43895
Expression System
HEK293 Cells
Tag
C-His
Sequence
His22-Ala650
Field of Research
Signal Transduction; Cell biology; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
71.6 kDa
Observed Molecular Weight
78 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Species
Human
Available Sizes
Documents
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