Recombinant Human ROBO4 Protein (Fc Tag)
Product Specifications
Background
Roundabout homolog 4 (ROBO4) contains 2 fibronectin type-III domains; 2 Ig-like C2-type (immunoglobulin-like) domains and belongs to the immunoglobulin superfamily.The protein is a receptor for slit proteins; at least for SLIT2; and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins.
Abbreviation
ROBO4
Synonyms
Magic roundabout; ROBO4; Roundabout homolog 4; UNQ421/PRO3674
UniProt
Q8WZ75
Accession Number
Q8WZ75
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Gln28-Arg467
Field of Research
Cardiovascular, Neuroscience, Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
74.6 kDa
Observed Molecular Weight
87 kDa
Species
Human
Available Sizes
Documents
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