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Recombinant Human HAO1 Protein (His Tag)

Product Specifications

Background

Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent α-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate; but it can also be active on 2-Hydroxy fatty acids; with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.

Abbreviation

HAO1

Synonyms

GOX; GOX1; Glycolate Oxidase; HAO1; HAOX1; Hydroxyacid Oxidase 1

Accession Number

Q9UJM8

Expression System

E.coli

Tag

N-Trx-His

Sequence

Met 1-Ile370

Field of Research

Signal Transduction; Tags & Cell Markers; Cardiovascular; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

58.6 kDa

Observed Molecular Weight

56 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Species

Human

Available Sizes

Curated Selection

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