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Recombinant Human Kallikrein 6/KLK6 Protein (His Tag)

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Abbreviation

Kallikrein 6; KLK6

Synonyms

KLK6; Kallikrein-6; Neurosin; PRSS18; PRSS9; Protease M; SP59; Serine Protease 18; Serine Protease 9; Zyme

UniProt

Q92876

Accession Number

Q92876

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu17-Lys244

Field of Research

Signal Transduction; Tags & Cell Markers; Cell biology; Neuroscience; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

26.2 kDa

Observed Molecular Weight

32&20&10 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 5mM HCl, 150mM NaCl.

Species

Human

Available Sizes

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