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Recombinant Human SECTM1 Protein (His Tag)

Product Specifications

Background

Secreted and Transmembrane Protein 1 (SECTM1) is a transmembrane and secreted protein that belongs to the SECTM family. SECTM1 is expressed in a perinuclear Golgi-like pattern. It is detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. SECTM1 is considered to participate in thymocyte signaling and the hematopoietic/immune system processes. It is reported that SECTM1 is a broadly expressed; IFN-γ-inducible molecule; which functions as a potent costimulatory ligand for T cell activation and is synergistic with anti-CD28.

Abbreviation

SECTM1

Synonyms

K12; Protein K-12; SECTM1; Secreted and Transmembrane Protein 1

UniProt

Q8WVN6

Accession Number

Q8WVN6

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln29-Gly145

Field of Research

Immunology, Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.8 kDa

Observed Molecular Weight

18-22 kDa

Species

Human

Available Sizes

Curated Selection

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