Recombinant Human IL1RL1/ST2 Protein (His Tag)

Interleukin 1 receptor-like 1 (IL1RL1) is a member of the interleukin-1 receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a receptor for interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 cytokine production, it directly implicated in the progression of cardiac disease.

FIT; DER; IL1RL; IL-1 R; IL1RL1; DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1; IL-1 R4; DER-4; FIT 1; Growth stimulation expressed; Growth stimulation expressed gene 2; homolog of mouse growth stimulation-expressed; IL-1R4; ILRL1; Interleukin 1 receptor like 1; interleukin 1 receptor related protein; Interleukin-1 receptor-like 1; Protein ST2; T1 protein

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.