Recombinant Human Resistin Protein (His Tag)
Product Specifications
Background
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM) . Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL) ; increasing the risk of heart disease; resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.
Abbreviation
Resistin
Synonyms
ADSF; Adipose tissue-specific secretory factor; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3; FIZZ3; HXCP1; RETN; RETN1; RSTN; Resistin; XCP1
Accession Number
Q9HD89
Expression System
E.coli
Tag
C-His
Sequence
Lys19-Pro108
Field of Research
Signal Transduction; Cardiovascular; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/5c4vqd
Product MSDS
https://789.bio/eb/8qbbfL
Calculated Molecular Weight
10.6 kDa
Observed Molecular Weight
10-14 kDa
Species
Human
Available Sizes
Curated Selection
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