Recombinant Human TEM8/ATR Protein (His Tag)
Product Specifications
Background
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton; it mediates adhesion of cells to type 1 collagen and gelatin; reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells; up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI) .
Abbreviation
TEM8; ATR
Synonyms
ANTXR1; ATR; Anthrax Toxin Receptor 1; TEM8; Tumor Endothelial Marker 8
UniProt
Q9H6X2
Accession Number
Q9H6X2-4
Expression System
HEK293 Cells
Tag
C-His
Sequence
Glu33-Lys321
Field of Research
Tags & Cell Markers, Microbiology, Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/eiu1oc
Product MSDS
https://789.bio/eb/GGu5y9
Calculated Molecular Weight
33.6 kDa
Observed Molecular Weight
35-45 kDa
Species
Human
Available Sizes
Curated Selection
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