Recombinant Human Calumenin Protein (aa 20-315, His Tag)
Product Specifications
Background
Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart; placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence; and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit γ-carboxylase GGCX.
Abbreviation
Calumenin
Synonyms
CALU; Calumenin; Crocalbin; IEF SSP 9302
UniProt
O43852
Accession Number
O43852
Expression System
HEK293 Cells
Tag
C-His
Sequence
Lys20-Phe315
Field of Research
Tags & Cell Markers, Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 82 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/tusg04
Product MSDS
https://789.bio/eb/POGO8K
Calculated Molecular Weight
36.0 kDa
Observed Molecular Weight
40-55 kDa
Species
Human
Available Sizes
Curated Selection
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