Recombinant Human Reticulocalbin 3/RCN3 Protein (aa 21-328, His Tag)
Product Specifications
Background
Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition; it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.
Abbreviation
Reticulocalbin 3; RCN3
Synonyms
EF-Hand Calcium-Binding Protein RLP49; RCN3; Reticulocalbin-3
UniProt
Q96D15
Accession Number
Q96D15
Expression System
HEK293 Cells
Tag
C-His
Sequence
Lys21-Leu328
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
36.2 kDa
Observed Molecular Weight
43 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 10% Glycerol, pH 7.4.
Species
Human
Available Sizes
Documents
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