Recombinant Human GMPR Protein (Human Cells, His Tag)
Product Specifications
Background
GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.
Abbreviation
GMPR
Synonyms
GMP Reductase 1; GMPR; GMPR1; Guanosine 5'-Monophosphate Oxidoreductase 1; Guanosine Monophosphate Reductase 1
UniProt
P36959
Accession Number
AAH08281.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Ser345
Field of Research
Signal Transduction; Cell biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
38.5 kDa
Observed Molecular Weight
40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 40% Glycerol, 150mM NaCl, 1mM DTT, pH 8.0.
Species
Human
Available Sizes
Documents
Frequently Asked Questions
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