Recombinant Human GGCT Protein (His Tag)
Product Specifications
Background
Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Abbreviation
GGCT
Synonyms
C7orf24; CRF21; Cytochrome C-Releasing Factor 21; GGCT; Gamma-Glutamylcyclotransferase
UniProt
O75223
Accession Number
O75223
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Leu188
Field of Research
Cell biology; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
23.2 kDa
Observed Molecular Weight
24-30 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Species
Human
Available Sizes
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